Botox vs. Dysport vs. Xeomin: What’s the Difference?

When it comes to softening fine lines and achieving a more youthful appearance, neuromodulators like Botox, Dysport, and Xeomin are trusted injectable treatments. While they all work similarly by relaxing facial muscles that cause wrinkles, there are subtle differences that may make one better suited to your individual needs.

At MDCS Dermatology, Estelle Hixon, PA-C specializes in aesthetic treatments, including Botox, Dysport, and Xeomin. Her goal is to provide personalized care that ensures natural-looking results tailored to your unique facial anatomy.

How Do These Injectables Work?

All three products are derived from botulinum toxin type A. They temporarily block nerve signals to the muscles, preventing repetitive movement that leads to wrinkles—most commonly on the forehead, around the eyes, and between the brows.

Botox

• FDA-Approved Since: 2002
  
  

• Best For: Forehead lines, crow’s feet, frown lines
  
  

• Onset: 3–5 days
  
  

• Duration: 3–4 months
  
  

• Notes: Botox is the most recognized and widely used brand. Its formulation contains accessory proteins which can influence how the body responds over time.
  
  

Dysport

• FDA-Approved Since: 2009
  
  

• Best For: Larger areas like the forehead
  
  

• Onset: 1–3 days (often faster than Botox)
  
  

• Duration: 3–4 months
  
  

• Notes: Dysport tends to spread more, which can be helpful for broader coverage but requires expert precision in application.
  
  

Xeomin

• FDA-Approved Since: 2010
  
  

• Best For: People who may have developed resistance to other neurotoxins
  
  

• Onset: 3–5 days
  
  

• Duration: 3–4 months
  
  

• Notes: Xeomin is a “naked” neurotoxin—meaning it has no added proteins. This may reduce the risk of developing resistance.
  
  

Choosing the Right Option

Each neuromodulator has its strengths. At MDCS Dermatology, your provider will assess your facial structure, muscle strength, and aesthetic goals before recommending the best option for you. Some patients prefer Botox’s track record, others find Dysport works faster, and some benefit from Xeomin’s purity.

Meet Estelle Hixon, PA-C

Estelle Hixon, PA-C brings a thoughtful, artistic approach to aesthetic dermatology. Her training and experience allow her to select and administer the right neuromodulator for each individual, always with a goal of enhancing natural beauty—not altering it.

Ready to Refresh Your Look?

If you’re considering Botox, Dysport, or Xeomin, schedule a consultation to determine which option is best for you.