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How Botox Works Differently in the Upper vs. Lower Face

Dec 26, 2025

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Botox smooths wrinkles and enhances facial contours differently in the upper and lower face. At MDCS Dermatology, Estelle Hixon, PA-C tailors treatments for natural, balanced results — softening forehead lines, crow’s feet, jawlines, and neck bands safely/

Botox is one of the most versatile and popular non-surgical cosmetic treatments, yet its effects vary depending on the area of the face being treated. At MDCS Dermatology, our providers tailor each Botox treatment to target specific muscles for natural, balanced results. Estelle Hixon, PA-C is a skilled injector who specializes in using Botox to enhance the upper and lower face safely and effectively.

Botox in the Upper Face
The upper face includes the forehead, glabella (between the eyebrows), and crow’s feet around the eyes. Botox works here by:

  • Relaxing dynamic wrinkles caused by repeated facial expressions such as frowning or raising eyebrows

  • Smoothing forehead lines for a refreshed and youthful appearance

  • Softening crow’s feet without affecting natural smiling or eye movement

Targeting the upper face requires precision to maintain natural expressions. Too much Botox in the forehead, for example, can lead to a “frozen” look, which is why treatment by an experienced provider like Estelle Hixon, PA-C is essential.

Botox in the Lower Face
The lower face includes areas around the mouth, jawline, and neck. Botox works differently here:

  • Jawline slimming and contouring: Botox can relax the masseter muscle, softening the jawline and reducing teeth grinding (bruxism)

  • Lip lines and corners of the mouth: Targeted injections help reduce “marionette lines” or downturned corners

  • Neck bands (platysmal bands): Botox can relax vertical neck muscles, smoothing the appearance of the neck

Lower face Botox requires careful dosing because these muscles are involved in speech, chewing, and facial expressions. Over-treatment can interfere with function, so expertise is crucial.

Combining Upper and Lower Face Treatments
Many patients achieve the most harmonious results by combining upper and lower face Botox treatments. During a consultation at MDCS Dermatology, Estelle Hixon, PA-C assesses facial anatomy, muscle activity, and aesthetic goals to create a customized plan that balances lift, smoothness, and natural expression.

Preparing for Your Botox Treatment

  • Avoid anti-inflammatory medications or alcohol before treatment to reduce bruising

  • Discuss prior Botox treatments and any medical history with your provider

  • Expect minimal downtime, with results appearing within 3–7 days and lasting 3–6 months

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