MDCS logo

How Collagen Production Changes After 40—And What You Can Do About It

Aug 01, 2025

misc image
Collagen loss accelerates after age 40, leading to wrinkles, sagging, and thinning skin. Dr. Regina Yavel at MDCS Dermatology offers personalized treatments like microneedling, lasers, and skincare to rebuild collagen and restore firmness.

As we age, one of the key structural components of youthful skin—collagen—begins to decline. After the age of 40, collagen production slows significantly, leading to thinner skin, fine lines, sagging, and a loss of elasticity.

At MDCS Dermatology, Regina Yavel, MD, FACMS, FAAD helps patients understand and address these changes with customized, evidence-based treatments that stimulate collagen and restore skin health.

What Is Collagen and Why Is It Important?

Collagen is a protein that forms the foundation of skin strength and structure. It supports skin elasticity, hydration, and firmness. Starting in your mid-20s, collagen levels drop by about 1% per year—and this decline accelerates around age 40.

Signs of Collagen Loss

  • Fine lines and wrinkles

  • Loss of skin firmness

  • Thinner, more fragile skin

  • Hollow areas in cheeks or under the eyes

  • Increased dryness or dullness

How to Boost Collagen After 40

  1. In-Office Treatments

    • Microneedling with PRP: Stimulates natural collagen production.

    • Laser Resurfacing: Improves texture and firmness.

    • Injectables: Can restore volume while supporting skin structure.

  2. Medical-Grade Skincare
    Products containing retinoids, peptides, and antioxidants help protect and rebuild collagen.

  3. Lifestyle Changes
    Sun protection, a protein-rich diet, sleep, and avoiding smoking are all essential.

Expert Guidance from Dr. Regina Yavel

Dr. Regina Yavel is a board-certified dermatologist and fellowship-trained Mohs surgeon with extensive experience in skin aging and rejuvenation. She offers a personalized approach to restoring skin integrity and vitality.

Book Your Consultation

Whether you're looking to prevent early signs of aging or correct visible changes, MDCS Dermatology offers a full range of collagen-boosting options.

Book Online