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PRP vs. Topical Treatments: Which Is More Effective for Hair Thinning?

Sep 12, 2025

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PRP uses your body’s platelets to stimulate dormant hair follicles, while topical treatments improve blood flow and slow shedding. At MDCS Dermatology, Dr. Lauren Penzi tailors plans combining both for optimal hair restoration results.

Hair thinning affects millions of men and women at different ages and can significantly impact self-confidence. At MDCS Dermatology, Lauren Penzi, MD offers expert insight into two of the most popular approaches to managing hair loss: PRP (Platelet-Rich Plasma) therapy and topical treatments.

Understanding PRP Therapy

PRP therapy uses your own blood’s platelets to stimulate hair follicles. A small sample of your blood is drawn, processed to concentrate the platelets, and then injected directly into areas of thinning hair. The growth factors in PRP promote stronger, thicker hair growth by rejuvenating dormant follicles.

Key Benefits of PRP Therapy:

  • Uses your body’s natural healing mechanisms

  • Stimulates dormant follicles for thicker, healthier hair

  • Minimal downtime and non-surgical

  • Suitable for both men and women

Dr. Penzi emphasizes that PRP works best for individuals in the earlier stages of hair loss, as it focuses on reactivating existing follicles rather than creating new ones.

Understanding Topical Treatments

Topical treatments—such as minoxidil and prescription-strength formulas—are applied directly to the scalp to encourage hair growth. These treatments increase blood flow to hair follicles, extend the growth phase of hair, and can slow down shedding.

Key Benefits of Topical Treatments:

  • Easy to apply at home

  • Affordable and widely accessible

  • Proven to help slow hair loss and stimulate regrowth

However, topical treatments require consistent, long-term use. Results may be more subtle compared to PRP, especially in advanced hair thinning.

Combining PRP and Topical Treatments

For many patients, combining PRP with topical treatments can produce the best results. PRP provides a regenerative boost while topical treatments maintain and prolong the growth cycle between PRP sessions.

Dr. Penzi’s Approach at MDCS Dermatology:
Every patient’s hair loss journey is unique. Dr. Penzi carefully evaluates factors like age, type of hair loss, and medical history to design a personalized plan—whether it’s PRP, topical therapy, or a combination of both.

What to Expect from Treatment

  • PRP Sessions: Typically 3–4 sessions spaced a month apart, followed by maintenance treatments every 6–12 months.

  • Topical Treatments: Daily use is recommended for ongoing benefits.

  • Results Timeline: Visible improvement may begin within 3–6 months, with continued growth over time.

Is PRP or Topical Therapy Right for You?

If you’re unsure which approach suits your needs, a consultation at MDCS Dermatology with Lauren Penzi, MD can help you choose the right path to healthier, thicker hair.

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